Six reasons why your nipples might hurt Nipples are very sensitive to both stimulation and irritation. When they hurt, it might get too uncomfortable to even put on a bra. And while the soreness doesn’t necessarily mean something serious, sometimes it could be a medical condition that should not be ignored. Here are some reasons why your nipples might be hurting: Allergic reactions Since they are very sensitive, nipples could react from chemicals from soaps, lotions, fabric, or laundry detergents. So if you notice that your nipples are hurting after changing your...